Red ginseng polysaccharide alleviates cytotoxicity and promotes anti-inflammatory activity of ginsenosides

Although Ginsenosides are a major physiological component of red ginseng (RG), some isolated ginsenosides known to have cytotoxic activity. This study was intended reduce cytotoxicity and promote anti-inflammatory activity by mixing the crude (RG-CG) polysaccharides (RG-CP). RG-CG-CM, fractionated from RG-CG, not only had higher than that RG-CG at 100 μg/mL, but also showed increased cytotoxicity, while RG-CP-4P RG-CP-8P, RG-CP, no cytotoxicity. To without affecting high RG-CG-CM were mixed in ratio 2:8. The significantly concentration 75 observed. A combination RG-CP effectively reduced enhanced specifically fraction, providing scope for its industrial application.